Abstract: In this paper is aim to design a new software tool that allows to create synthetic biology complex systems and genetic circuit designs, as well as to carry out the development of these models using a wide set of biological and biochemical rules. Thus, it will keep a very close relationship respect to the real characteristics of the biological systems and their environment, obtaining then a high reproducibility in the progress and simulation systems in relation to the progress of the real experiment. It will describe a comparison between two software tools which allow us to design, build and simulate synthetic biology networks and biochemical processes. The progress, improvement and combination of the distinct possibilities that offer both software as well as the analysis of a joint usage of them will result the creation of the new software.

Keywords: synthetic biology, natural computation, COPASI, SynBioSS?, biological systems, synthetic biology,in silico, in vivo, in vitro, BioBricks?, SBML, XML, repressilator.

ACM Classification Keywords: D.2 SOFTWARE ENGINEERING, H.2 DATABASE MANAGEMENT J.3 LIFE AND MEDICAL SCIENCES, I.6 SIMULATION AND MODELING, J.2 PHYSICAL SCIENCES AND ENGINEERING.

Link:

BIOLOGICAL PROCESSES STUDIES THROUGH SOFTWARE TOOLS: DEVELOPMENT AND OPTIMIZATION IN THE SIMULATION OF SYNTHETIC BIOLOGICAL CONSTRUCTIONS

Perceval Vellosillo, Roberto Tomé, Verónica Llorens-Rico?, Juan B. Castellanos

http://www.foibg.com/ijitk/ijitk-vol07/ijitk07-01-p03.pdf